PT-141

A melanocortin-receptor peptide tested in phase 3 trials for low desire in women; an independent re-analysis found the benefit modest.

Randomised trial2 studies2 min readUpdated 2 Oct 2026

How does it work?

PT-141 (bremelanotide) activates melanocortin receptors in the brain rather than acting on blood flow.

What does the research say?

Published studies, strongest evidence first.

  • Randomised trial

    Two phase 3 trials in 1,267 premenopausal women: desire scores rose slightly more than on placebo; nausea, flushing and headache were more common.

    Obstet Gynecol, 2019 · PubMed
  • Review

    An independent re-analysis of the same trials found the benefits modest and dropouts from side effects much higher than on placebo.

    J Sex Res, 2021 · PubMed

What should you know?

  • There are randomised trials in people, the strongest kind of evidence.
  • For research and education, not medical advice. Talk to a health professional before using any peptide.

Frequently asked questions

What is PT-141?

A melanocortin-receptor peptide tested in phase 3 trials for low desire in women; an independent re-analysis found the benefit modest.

How strong is the evidence for PT-141?

There are randomised trials in people, the strongest kind of evidence. This summary covers 2 published studies, each labelled by study type.

Is PT-141 registered with BPOM?

No. PT-141 from Continue is a research-grade compound, not a medicine, and is not registered with BPOM.

Where can I buy PT-141 with a COA in Indonesia?

Continue sells research-grade PT-141 with a COA for every batch, shipped cold across Indonesia.

PT-141
Available at ContinuePT-141From Rp 1.300.000 Rp 1.625.000
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Tested in an Indonesian research institution.

Every batch we ship has undergone testing at a university laboratory or an independent research institution in Indonesia. A Certificate of Analysis is available for every order.

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