Kisspeptin

A natural hormone that starts the reproductive hormone chain; placebo-controlled human studies look at desire and brain activity.

Randomised trial3 studies2 min readUpdated 2 Oct 2026

What are the key numbers?

+56%arousal response versus placeboUp to 56%, in 32 men with low sexual desireRandomised trialPubMed

How does it work?

Kisspeptin acts on the KISS1 receptor in the brain, which triggers GnRH and then LH and FSH release.

What does the research say?

Published studies, strongest evidence first.

  • Randomised trial

    Placebo-controlled crossover in 32 men with low sexual desire: kisspeptin changed activity in the brain's sexual-processing network and raised arousal response by up to 56% versus placebo.

    JAMA Netw Open, 2023 · PubMed
  • Randomised trial

    Placebo-controlled crossover in 32 premenopausal women with low sexual desire: kisspeptin changed sexual and attraction brain processing and was well tolerated.

    JAMA Netw Open, 2022 · PubMed
  • Human study

    In 29 healthy young men, kisspeptin increased limbic brain activity in response to sexual and bonding images and eased negative mood.

    J Clin Invest, 2017 · PubMed

What should you know?

  • There are randomised trials in people, the strongest kind of evidence.
  • For research and education, not medical advice. Talk to a health professional before using any peptide.

Frequently asked questions

What is Kisspeptin?

A natural hormone that starts the reproductive hormone chain; placebo-controlled human studies look at desire and brain activity.

How strong is the evidence for Kisspeptin?

There are randomised trials in people, the strongest kind of evidence. This summary covers 3 published studies, each labelled by study type.

Is Kisspeptin registered with BPOM?

No. Kisspeptin from Continue is a research-grade compound, not a medicine, and is not registered with BPOM.

Where can I buy Kisspeptin with a COA in Indonesia?

Continue sells research-grade Kisspeptin with a COA for every batch, shipped cold across Indonesia.

Kisspeptin
Available at ContinueKisspeptinFrom Rp 1.700.000 Rp 2.125.000
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