Tirzepatide

A dual GIP and GLP-1 receptor agonist with large phase 3 trials in adults with obesity.

Randomised trial1 study2 min readUpdated 2 Oct 2026

What are the key numbers?

-20.9%body weight at week 72, highest-dose groupPhase 3 trial in 2,539 adults with obesity; placebo -3.1%Randomised trialPubMed
91%lost at least 5% of body weightHighest-dose group at week 72; placebo 35%Randomised trialPubMed

How does it work?

Tirzepatide acts on two gut-hormone receptors, GIP and GLP-1, that signal fullness and help regulate blood sugar after meals.

What does the research say?

Published studies, strongest evidence first.

  • Randomised trial

    Phase 3 SURMOUNT-1 trial in 2,539 adults with obesity: weight fell 15.0% to 20.9% over 72 weeks depending on the group, versus 3.1% on placebo.

    N Engl J Med, 2022 · PubMed

What should you know?

  • There are randomised trials in people, the strongest kind of evidence.
  • For research and education, not medical advice. Talk to a health professional before using any peptide.

Frequently asked questions

What is Tirzepatide?

A dual GIP and GLP-1 receptor agonist with large phase 3 trials in adults with obesity.

How strong is the evidence for Tirzepatide?

There are randomised trials in people, the strongest kind of evidence. This summary covers 1 published studies, each labelled by study type.

Is Tirzepatide registered with BPOM?

No. Tirzepatide from Continue is a research-grade compound, not a medicine, and is not registered with BPOM.

Where can I buy Tirzepatide with a COA in Indonesia?

Continue sells research-grade Tirzepatide with a COA for every batch, shipped cold across Indonesia.

Tirzepatide
Available at ContinueTirzepatideFrom Rp 5.400.000 Rp 6.750.000
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